Sentence examples for alterations has provided from inspiring English sources

Analysis of gene alterations has provided invaluable insight that has spurred the development of targeted therapies for NSCLC.

In addition to biomechanical alterations associated with the pathomechanisms underlying PFP, the investigation of neurophysiological alterations has provided novel information in the understanding of the pathophysiology of PFP.

The ability to trace nutrient fluxes in the context of specific alterations has provided new mechanistic insight into the process of oncogenic transformation.

Understanding histologic subtypes and associated molecular alterations has provided the framework within which diseasespecific therapy has developed.

Also epigenetic alterations have provided a potential cancer marker, which could be used for the early examination as well as prediction of therapeutic responses [7].

These alterations have provided unique opportunities for discovery, as they have sometimes led to a splitting of regulatory elements.

Standard chemotherapy using gemcitabine or targeted therapies directed at molecular alterations in cancer cells has provided almost no survival benefit in clinical trials, despite cytostatic results in in vitro and in vivo preclinical PDAC models (Hidalgo & Von Hoff, 2012).

Research into cancer-specific alterations in glycosylation of serum glycoproteins has provided a promising source of novel biomarkers.

The analysis of genetic alterations in ductal carcinoma in situ (DCIS) has provided new insights in the biology of these lesions.

Comprehensive analysis of cancer genomes has provided important insights in the critical alterations that confer proliferation and survival advantage to the tumor, so-called driver mutations.

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