Sentence examples for alterations gene expression from inspiring English sources
Because all subjects were unmanipulated adult males, we cannot be certain that observed effects result from testosterone action, or if so, whether ongoing stimulation with testosterone is required for the alterations gene expression.
We conducted an analysis integrating multiple genomic features including mutations, copy number alterations, gene expression and methylation.
We compiled multiple genomic data types (mutations, copy number alterations, gene expression and methylation status) as well as clinical meta-data from The Cancer Genome Atlas (TCGA).
Curtis and colleagues [ 2] revealed new biological subgroups as integrative clusters, characterized by well-defined copy number alterations, gene expression, and distinct clinical outcomes.
Studies have identified chromosomal alterations, gene expression changes, and aberrant promoter methylation associated with cervical cancer (CC) [ 10], but little is known about the specific role of miRNAs.
For example, medulloblastoma (MB) consists of four distinct subtypes – called WNT, Sonic Hedgehog (SHH), Group 3 and Group 4 – which exhibit different genomic alterations, gene expression profiles and response to treatment.
Here, we performed an integrated genomic and transcriptomic analysis of 41 TDRD genes in breast cancer (TCGA and METABRIC datasets) and identified associations among recurrent copy number alterations, gene expressions, clinicopathological features, and survival of patients.
Thus, temperature alterations can change gene expression through dADAR concentration.
Although this classification is mainly based on histopathology, taking into account differences in the composition of the reactive infiltrate and stroma, recent studies have demonstrated that these disease entities are biologically different, with different genomic alterations, gene-expression patterns, cytokine milieu, and clinical behavior [ 6, 7].
While culturing the cells introduces its own alterations in gene expression, these alterations are uniform across samples.
As discussed earlier, many alterations in gene expression suggest an alteration in calcium homeostasis in NPC cells (Table 3).
