The phrase "alterations frequently" is correct and usable in written English.
It can be used when discussing changes or modifications that occur often or regularly.
Example: "In our design process, we find that alterations frequently lead to improved outcomes."
Alternatives: "changes often" or "modifications regularly".
Mutations in p53 and RAS potently cooperate in oncogenic transformation, and correspondingly, these genetic alterations frequently coexist in pancreatic ductal adenocarcinoma (PDA) and other human cancers.
In the last three decades, technological advances have facilitated the generation of genetically engineered mouse models (GEMMs) to mimic the alterations frequently observed in human cancers or to conduct intervention studies and assess the relevance of candidate gene networks in tumor establishment, progression and maintenance.
Interestingly, several miRNA alterations frequently observed in lung cancers, such as down-regulation of let-7 and over-expression of miR-17-92 miR-17-92 miR-17-92ncer stem cells [17], [18] arewell as pseudetectedlar lung parenchyma [19], suggesting embryonicancerogramming of miRNA exprestemn during pulmonary cellsnogenesis.
PI3K pathway alterations frequently co-occur in breast cancer, suggesting that they confer advantages to cancer cells by different mechanisms.
Genomic instability has been characterised in many human cancers and its signature is the pattern of sequence alterations, frequently resulting in allelic imbalance.
Both experimental and observational studies provide good evidence to conclude that microbial alterations frequently observed in IBS patients potentially drive or perpetuate gastrointestinal symptoms.
The deletion at chromosome 9p21 removing the p16 tumor suppressor gene is a genetic alteration frequently observed in a variety of human cancers.
One alteration frequently mentioned as the type of thing landmark regulation would not permit is an immaculately tasteful reconstruction of the little projecting vestibule of the old Gordon Whyte house.
Loss of multiple chromosomal regions is another genetic alteration frequently found in lung tumours.
Since SOX2 is a target of amplification in different tumors, we hypothesized that this genetic alteration, frequently associated with tumor progression, could explain not only the expression but also the heterogeneity of SOX2.
Deletions at 9p21 deserve attention because removal of the p16 tumor suppressor gene is a genetic alteration frequently observed in a variety of human cancers (Drexler 1998; Ruas and Peters 1998; Orlow et al. 1999; Bertin et al. 2003; Irving et al. 2005; Murao et al. 2006; Kohno and Yokota 2006; Strefford et al. 2007; Usvasalo et al. 2008; Bungaro et al. 2009).
