Sentence examples for alterations derived from from inspiring English sources

The Tableau Desktop business intelligence software [ 12] was employed to create an interface that displays the frequency/location of particular amino acid alterations derived from gene mutations identified within the TCGA UCEC sample set overlaid upon the frequency/location of particular amino acid alterations derived from mutations within the same gene within the COSMIC database version 66 [ 6].

One of the more intriguing hypotheses about aging and age-related disease is that age-associated phenotypic alterations derive from the inability of resident stem cells to maintain tissue structure and function [ 54].

Although the structural alteration derived from the missense point mutation eradicates the DNA binding activity of IRF-5P68, it does not remarkably alter other protein properties because this mutant like its wild type predominantly localizes in the cytosol and dynamically shuttles between cytoplasm and nucleus in resting cells.

These ECM alterations derived, at least partly from decreased SLRP levels and enhanced MMP activity within the myocardium.

Next-generation sequencing from the BOLERO-2 trial has demonstrated that patients with a minimal number of genetic alterations derived the greatest benefit from everolimus, suggesting that concomitant mutations in other oncogenic pathways might mediate resistance or attenuate everolimus efficacy [ 38].

Unlike other tumor biomarkers, the specificity of somatic alterations is derived from the fact that mutations are present in the genome(s) of tumor cells but not in the genome of matched normal cells.

Despite that the aforementioned authors describe alterations of the thalamus in context of its connectivity with the temporal lobe, all evidence of thalamic structural alteration was derived from T1-weighted MRI scans only, which provides very little if any information on brain connectivity.

This scheme includes not only information about the internal structure but also information related to the extension and location of the magma chambers, the hydrogeology and the hydrothermal alteration products derived from the geothermal system.

This study applied flow duration curves and three performance indices as well as a method of statistical testing to identify whether Indicators of Hydrologic Alteration (IHA) derived from historical and synthetic flow data have the same distribution.

To identify the genomic alterations for the differentially expressed genes discovered in this project, we took the advantage of the TCGA database, containing recently published large mRNA expression and genomic alteration data, derived from 195 stage I IV CRC patients [ 20].

A recent report indicated miRNA profile alterations in PBMCs derived from MG patients.