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It is possible that the R337H mutation in combination with these polymorphisms and possibly other genetic alterations creates a p53-insufficient state that enhances tumor susceptibility.
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For this purpose, wellbore flow rate has changed, and these alterations create a wavy pressure inside the reservoir.
These age-associated alterations create a metabolically active microenvironment, especially in the thickened intima, and render it fragile, and vulnerable to pathologic stimuli, e.g., a high cholesterol diet, in older persons [1] [7 ]
Together, these alterations create a global, interconnected, and integrated network that leads to a general loss of SKM mass due to the inability of muscles to function, respond to, and repair damage and injury.
The current primary concept for the molecular basis of evolution involves genetics and mutations, such that random DNA sequence and chromosomal alterations create a genetic variation that directly impacts phenotype and phenotypic variation.
Here, we summarize the foundation of such a paradigm on the origins of cancer, in which metabolic alterations create an epigenetic progenitor that clonally expands to become cancer.
This is not a conserved ORF and it may have arisen recently from a single base pair alteration that creates a UGG codon for tryptophan, in place of the UGA-termination codon found in other primate genomes (Figure S4).
With regard to phase one, route alterations had been made that had not been subject to consultation, even though in a number of instances "these alterations create greater impacts on individual properties and the environment than was previously the case".
Since vocal therapy is one of the first noninvasive treatment options with potential to help the client to reacquire a functional voice, it is fundamental to know in detail the alterations created by the pathology at VF and vocal tract level to better guide the treatment.
This similarity suggests the possibility that human behaviors associated with exurban homes may play a larger role in shaping avian community characteristics nearby than do habitat alterations created by construction and clearing.
How many new antigenic epitopes do these alterations create?
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