Sentence examples for alterations contribute to from inspiring English sources

In some tumours, the biological activity, organization or expression of these genes is altered, suggesting that such alterations contribute to the development of neoplastic disease.

Genetic alterations contribute to the leukemic transformation of hematopoietic stem cells or their committed progenitors by changing cellular functions.

Changes in the cell population embody the characteristic of cancer plasticity, which could explain how genetic alterations contribute to EGFR or ALK resistance.

Genetic and epigenetic alterations contribute to prostate cancer formation, as with most other cancers.

These data suggest that metabolic alterations contribute to low insulin secretion in βlow-cells.

Many factors, such as chromosomal anomalies, genetic polymorphisms, genetic and epigenetic alterations, contribute to tumorigenesis and progression of urothelial carcinoma of the bladder [2].

Therefore, in this study univariate statistical test was used to determine gene alterations contributing to the increased level of resistance/sensitivity to a given drug.

New evidence suggests that physiological alterations contributing to chronic pain states take place both in the peripheral and central nervous systems.

These alterations contributed to neutralize the negative effects of tannic acid and maintain body mass in animals supplemented with tannic acid.

Recent studies investigating the genetic determinants of cancer suggest that some of the genetic alterations contributing to tumorigenesis may be inherited, but the vast majority is somatically acquired during the transition of a normal cell to a cancer cell.

These studies have determined that only a fraction of genetic alterations contributing to tumorigenesis may be inherited, while somatically acquired mutations can contribute decisively during the progression of a normal cell to a cancer cell.