The phrase "alterations cell cycle" is not correct in written English as it lacks proper grammatical structure.
It could be used in a scientific context, but it needs additional words to clarify its meaning, such as "alterations in the cell cycle."
Example: "The study focused on the alterations in the cell cycle that lead to cancer development."
Alternatives: "changes in the cell cycle" or "modifications to the cell cycle."
Change in cell viability could result from alterations in cell cycle, global transcription, post-transcriptional regulation, or translational efficacy.
While examining the alterations of cell cycle genes in early and advanced HCV, we found altered expression of mitotic checkpoint genes, MAD2L1, KNTC1, CDC16 and CDC34.
Additional pathways suggested include: endocrine disruption, suppression of hormone regulation and hormone mediated gene transcription, alteration of cell cycle kinetics, and alterations in cellular proliferative response that might play roles in association with carcinogenesis [ 37].
Given these protective roles against specific alterations in cell cycle and cell death resistance, many cancer-associated TP53 mutations have been identified.
Evidence of apoptotic induction and alterations in cell cycle characteristics were investigated using PI staining and FACS analysis, as described above.
Further studies revealed that manipulated expression of ST3GAL IV led to the significant alterations of cell cycle distribution, apoptotic signal, cell proliferation and the effectiveness of imatinib treatment.
The data demonstrated that A. montana and A. absinthium extracts protected NCTC cells against oxidative damage, supported cell proliferation and showed no alterations in cell cycle caused by H2O2-induced oxidative stress.
Moreover, this study demonstrated a reduction in overall CDK activity implying alterations in cell cycle biology.
Moreover, the nuclear changes seen during Raf/ERK activation were shown to correlate with alterations in cell cycle progression and the onset of p21 induced cell cycle arrest.
Comparison of transgenic and tumor networks supported our hypothesis of progressive alterations of cell cycle regulation as well as of lipid metabolism during hepatocarcinogenesis.
