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Furthermore, the receptor is subject to many post-translational modifications, and these alterations can affect receptor function at several levels.
Although the advantages of engineered therapeutic proteins are considerable, the alterations can affect the safety and efficacy of the drugs.
In addition to genetic alterations, epigenetic alterations can affect the cancer transcriptome more extensively.
In addition, genetic alterations can affect the enhancers themselves.
These alterations can affect the balance of gene regulation networks and thus the proliferation and survival of cells (Deng et al., 2011).
As ROS alterations can affect the intracellular redox state, we next measured the ratio of reduced to oxidized glutathione (GSH/GSSG) in WT and Jdp2 KO MEFs.
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The model predics how this alteration can affect synaptic plasticity and signal integration.
Not only can the loss of function be catastrophic, but also the sensory alteration can affect their ability to cope and deal with the healing process.
Sleep is a very important resource for recovery from daily stresses and strains, and its alteration can affect both mental and physical health [ 1- 6].
These subjective and semiquantitative studies have inspired subsequent investigators to assess genetic polymorphisms in the promoter regions of MMP genes, as this type of DNA sequence alteration can affect cancer susceptibility and malignant phenotype (Yasui et al, 2005).
SNPs are abundant sequence alterations that can affect gene function.
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