The phrase "alterations by both" is correct and usable in written English.
It can be used when discussing changes or modifications made by two parties or individuals.
Example: "The final design included alterations by both the client and the designer to better meet the project's needs."
Alternatives: "changes made by both" or "modifications from both".
Our data suggest that DCC alterations caused by both epigenetic and genetic alterations were significantly associated with gastric cancers exhibiting the CIN phenotype.
Similar to the DCC alterations in gastric cancer, our data highlight that UNC5C alterations caused by both epigenetic and genetic events were significantly associated with CIN-positive gastric cancers.
Since p70S6K is a downstream mediator of PI3K pathway, we explored gene expression alterations caused by both p70S6K and PI3K/mTOR pathway inhibitions.
Overall, the KEGG Atlas overview of intermediary metabolism provides an integrated gestalt of the global metabolic expression alterations caused by both mutation types and their substantial normalization with probucol therapy (Supporting information File 10).
Interestingly, the neuronal alterations provoked by both environmental contaminants in the present study seemed to coincide with changes of the histaminergic transcriptional activities in some telencephalic and mesencephalic regions and in the anterior and posterior areas of the hypothalamus.
Future study of intermediary metabolic flux alterations by isotopic profiling in both mutant types will be necessary to dissect whether the direction, rather than mere occurrence, of transcriptional alterations in multiple metabolic pathways is indicative of a specific adaptive response to primary mitochondrial dysfunction.
On CGH, the only alteration shared by both tumours was a gain of the long arm of chromosome 8, with amplification on this arm of chromosome 8 in the malignant recurrence.
The change in resistance during the adsorption or desorption process of H2 species is likely to be caused by the alteration both in the width of the surface depletion layer of each In2O3 nanotower and in the height of potential barriers built at the contacted junctions between two In2O3 nanotowers.
"What's absolutely fantastic are the alterations by Cuvellier," Mr. Léage said.
