The phrase "alterations at different" is not correct and lacks clarity in written English.
It may be intended to refer to changes or modifications occurring at various points or levels, but it needs additional context to be meaningful.
Example: "The alterations at different stages of the project were crucial for its success."
Alternatives: "changes at various" or "modifications at different points".
An increasing number of investigations suggest pathophysiological alterations at different levels of the neuroaxis, either alone or simultaneously within the peripheral or central nervous system, in the etiopathogenesis of primary BMS.
These studies support the idea that alterations at different hierarchical levels in bone are induced by in vivo mechanical stimulation.
In most studies, a large number of experimental animals are required to assess lung alterations at different stages of the disease.
One of the major advantages of HRM is for the detection of somatic mutations in genes that can have alterations at different positions in the coding sequence.
The co-occurrence and mutual exclusivity of copy number alterations at different loci may also reflect co-operating and complementary cancer genes, respectively.
These results, although contradicted with the previous report that majority of the mutations involved in homoplasmy to homoplasmy changes, were consistent with random occurrence of mtDNA alterations at different times during tumorigenesis, or, mutations that might become homoplasmic at different rate.
In an attempt to determine the kinetics of spermatogenesis regeneration after irradiation in both WT and KO mice, we searched for testis alteration at different age after irradiation (2 Gy) at the time of spermatogonial stem cells establishment (P3).
Using these and our own markers (Table 1) we found two major alterations occurring at different evolutionary stages of diploid wheats.
The alterations can occur at different levels: mutation, copy number variations or gene translocations resulting in altered expression of the corresponding genes or impaired protein functions.
Epigenetic alterations may occur at different stages of tumorigenesis and malignant progression [6], [7], but some researchers believe that aberrant methylation takes place before genetic alterations.
The genetic alterations were applied at different points as shown in Figure 1 where the time points are labeled T = 1,2,..,12.
