Sentence examples for alterations at both from inspiring English sources

Epigenetic alterations at both the DNA and histone level are increasingly being recognised as playing a role in tumourigenesis.

Only few of those studies have taken into account the importance of uraemia-induced alterations at both systemic and peritoneal levels.

The MapMan analysis indicated that some metabolic pathways were changed by allelic alterations at both loci, GS3 and qGL3 (Fig.  4a).

In any event, the possibility of impaired dysbindin function leading to alterations at both presynaptic and postsynaptic terminals (see below) merits consideration.

The malignant transformation of precancerous colorectal lesions involves progressive alterations at both the molecular and morphologic levels, the latter consisting of increases in size and in the degree of cellular atypia.

Evidence from various molecular and genetic studies suggests an association between squamous cell carcinoma initiation and development and the accumulation of genetic alterations at both the DNA and RNA levels [ 3].

A series of time points measured at hourly intervals will be required to follow substantial short-term alterations both at the mRNA and protein level.

Alterations occurred at both protein and RNA levels and at post-translational phosphorylation modifications.

The insulin resistance is responsible for numerous alterations both at the metabolic and cellular levels.

These included aberrant hypomethylation in adjacent normal liver tissue, tumor-specific hypermethylation, and the frequent occurrence of both genetic and epigenetic alterations at 11p15.5 and 20q13.3 loci.

Another important finding was the frequent occurrence of both genetic and epigenetic alterations at the two chromosomal loci, 11p15.5 and 20q13.3.