Sentence examples for alterations associated to from inspiring English sources

d genetic alterations associated to the cell line.

Information on gene alterations associated to poorly differentiated (PDTC) and anaplastic thyroid carcinomas (ATC) is scarce.

Taken together, these data could be an important resource in understanding the epigenetic alterations associated to CRC.

We evaluated transcriptome alterations associated to DNA helical stress from the transcript ratios of the sir3 strains as above (top2 ts versus TOP2).

In the present study, we analyzed DNA hypermethylation on the promoter sequences of a panel of cancer-related genes in order to investigate epigenetic alterations associated to this process.

In order to improve our knowledge of lung cancer biology in non-smokers, one of the first questions to answer is: what are the molecular alterations associated to EGFR mutations in lung cancer?

Initially, we were interested in epigenetic alteration associated to the disease-related gene mutations of LMNA or WRN.

Sanger sequencing of the region and 1.2 kb flanking interval (chr4:4863673–4864873) did not reveal any genetic alteration associated to the hypermethylation state.

For this purpose, we firstly assayed whether paclitaxel treatment of PSPs and control clones (CCs) sublines induced alterations typically associated to aneuploidy appearance (chromosome missegregation and apoptosis defect).

The classical criteria of assigning a pathogenic condition to any de novo alteration cannot be always applied, as exceptions in both senses can occur: benign copy number variants (CNVs) can arise de novo (unpublished results) while some pathogenic alterations are associated to such a broad phenotypic spectrum that they may have been inherited from apparently healthy parents [ 1].

The most discriminative terms related to the Cellular Component sub-ontology refers to DNA-repair complexes MutSalpha and MutSbeta, to lysosome and lytic vacuoles, involved in apoptosis and tumour suppression processes [ 15], and to catenin complex, a key regulator of the Wnt signalling pathway whose alterations are associated to carcinogenesis [ 16].