Sentence examples for alterations are represented from inspiring English sources
The main epigenetic mechanisms responsible for these alterations are represented by DNA methylation, posttranslational histone modifications, and regulation by noncoding microRNAs [ 4].
The main molecular alterations are represented by variations in gene expression, usually mild and with consequences for a vast number of target protein coding genes.
One of the most relevant alterations is represented by the p16 (CDKN2A -CCNDs/CDK-Rb pathway frequently altered in various types of CDKN2A -CCNDs/CDK-Rb
These alterations were represented by changes in liver echogenicity, in the relationship between liver parenchyma and renal cortex echogenicity, increased values of PVD and higher incidence of ascites when compared to the Control group (Table 1).
Alteration levels are represented by the variable Y (1: for the reference databases; 2, 3 and 4: for the altered databases levels 1, 2, and 3).
Changes in physiological functions are represented by alterations in profiles of neuropeptides that can be investigated by neuropeptidomic approaches in health and disease.
However, it remains uncertain whether genomic alterations existing in primary tumor tissues are represented in cell lines and whether cell lines carry cell line-specific genomic alterations.
Despite the identification of several rare genetic variants associated to disruption of spermatogenesis, so far, the only two categories of genetic alterations responsible for a significant portion of cases of male infertility, and thus commonly tested in the clinical practice, are represented by chromosomal alterations and Yq microdeletions [ 5– 10].
Alteration of copy number for Chr1, 2 and 3 are represented at similar frequencies based on the average copy number alteration of all five chromosomes, with Chr4 and 5 alterations being, respectively, over- and under-represented.
Figure 1A represents a typical slide from saline-treated rats, in which no morphologic alterations are present.
A complete loss of rhythmicity or a change of phase of the rhythms are the most frequent alterations, but another important factor is represented by the change of levels and amplitude of variation.
