Sentence examples for alterations are needed for from inspiring English sources

The notion that only a portion of melanocytes with activated ERK will develop melanoma, suggests that the ERK activation is an initial event in GHM genesis and additional alterations are needed for progression to melanoma.

Nevertheless, the presence of a persistent high-risk HPV infection risk is not sufficient to immortalize and transform the epithelial cells of the host; it has been confirmed that the presence of genetic and epigenetic alterations are needed for the development of carcinogenesis.

CV is normally very stable presumably due to the existence of a conduction reserve and therefore large alterations are needed to slow CV (for review see [ 8]).

DNA alterations are necessary for the evolution by natural selection 7. DNA alterations are necessary for speciation 8. DNA alterations are needed to cause species diversity.

Appropriately designed trials enriched for patients with HER2 alterations are needed to determine whether HER2-targeted therapies provide benefit.

Nonetheless, large alterations are needed to achieve low BER values.

Thus no alterations are needed in the global system assembly described in reference [1].

Adaptation includes alterations of genes that are needed for cellular survival in their new environment.

Our data indicate that the hemadsorption site serves to enhance the catalytic efficiency of NA and they suggest that, in addition to changes in the receptor-binding specificity of the hemagglutinin, alterations of the NA are needed for the emergence of pandemic influenza viruses.

Antioxidants, vitamins, minerals, and trace elements are needed for the normal metabolism of neurotrophic factors, eicosanoids, and neurotransmitters, supporting reports of their alterations in autism.

Because detailed analysis of the DFMs in lms mutant flies showed that the DFMs are present and lack any overt morphological alterations, it appears that lms is needed for the acquisition of the requisite functional properties of these muscles rather than their formation and morphogenesis.