Sentence examples for alterations are mediated from inspiring English sources

Consistent with this idea, intracerebroventricular and hypothalamic leptin administration alters hepatic glucose fluxes and glucose production [6], [7], and such alterations are mediated in part via the intact hepatic vagus nerve [10].

Such cell cycle alterations are mediated by p53 and p21.

Emerging evidence demonstrates that a significant proportion of these alterations are mediated by hormone imbalances.

Such reversible gene-based alterations are mediated by a process referred to as epigenetics.

These results clearly indicate that the Nef-induced signaling activation and phenotypic alterations are mediated by TAK1, in both M2 and M1-M Φ.

However, the marginal increase in G1-phase observed in the present study does not fit with this hypothesis, and the effects on mRNA and protein expression suggest that TS alterations are mediated by mechanisms involving transcriptional regulation.

In addition, IRE1 α-KD-induced [Ca2+]i alterations were mediated by InsP3R.

The level of progression for the processes of epigenetic genome-wide alterations that are mediated by DNA methyltransferases (DNMTs 1o and 3a/3b) and histone deacetylases (HDACs) can be modulated (i.e., reversed) via exogenous inhibitors of these enzymes throughout in vitro culture of nuclear donor cells and/or cloned embryos [ 19, 36– 36].

The intracellular flux distribution alterations in general are mediated through transcriptional, protein level and metabolic regulation, the fluxes being the integrated network response of the regulated interactions between enzymes and metabolites [ 4].

In particular, Grenon et al. suggested that the alterations in NO production are mediated by changes in the cytoskeleton detected in all the endothelial types studied [ 29].

In addition, the nuclear shape alterations, characteristic of senescence, are mediated through lamin B1 upregulation, in a p38 dependent manner [ 24].