Sentence examples for alterations are found from inspiring English sources

Study of the molecular biology of these tumors has revealed that the most frequent alterations are found in genes related to regulation of gene transcription, those regulating the cell cycle, and genes maintaining genome stability.

These alterations are found at high frequencies (up to or greater than 90%) in rare cancer types (secretory breast carcinoma, mammary analogue secretory carcinoma, cellular or mixed congenital mesoblastic nephroma and infantile fibrosarcoma) and at lower frequencies (commonly <1%) in a range of other tumour types.

While large numbers of epigenetic alterations are found in cancers, the epigenetic alterations in DNA repair genes, causing reduced expression of DNA repair proteins, appear to be particularly important.

Similar genetic alterations are found frequently in esophageal biopsy specimens from patients with various stages of neoplasia in Barrett's esophagus.

For instance, while EGFR mutations or copy number alterations are found in nearly 50% of all glioblastomas [1], [2], EGFR inhibition has yet to yield significant improvements in clinical outcome [3].

Numerous genetic and epigenetic alterations are found in urothelial bladder cancers (Wu, 2005; Mitra and Cote, 2009).

In gliomas, a consistent pattern of chromosomal alterations were found involving altered regions which harboured seven "landscape genes" associated with patient survival, among these POLD2 [18].

No microsatellite alterations were found in MN and AK.

Two main structural alterations were found to broaden the spectrum of biological activity in most cases.

Unilateral and bilateral irritative peripheral vestibular alterations were found in 67.4% of the underperformers and in 26.7% of the children not experiencing difficulties at school.

Several pronounced alterations were found in the spleen architecture, as manifested by irregular features within the capsule and medulla, namely depletion of T4 and B cells.