Sentence examples for alterations are essential for from inspiring English sources

Identification and characterization of genetic alterations are essential for diagnosis of multiple myeloma and may guide therapeutic decisions.

Several obvious goals for future research will be to define the function of myb proteins within the nucleus, to understand the regulation of myb expression during the cell cycle, to establish which molecular alterations are essential for converting c-myb into a transforming gene, and the determine the role of myb in human malignancies.

Precise identification of genomic alterations is essential for personalized therapy in cancer.

Therefore, better understanding of the pathogenesis and identification of the molecular alterations is essential for the development of useful indicators that aid novel effective therapies for gastric cancer [ 3- 5].

The early detection of risk factors for the occurrence of these alterations is essential for a better understanding of the problem and may lead to the development of appropriate prevention and control strategies.

Consideration of drug physicochemistry and protein binding, CRRT settings and disease-related pharmacokinetic alterations is essential for individualizing dose regimens with the purpose of attaining pharmacodynamic targets associated with success.

Identifying these alterations is essential to understanding the mechanisms of cancer progression, and will enable the development of more effective methods for diagnosis and treatment.

These results suggest that alterations of this pathway are essential for the oncogenic process of the different subtypes of LPS.

First, the synergistic effect of AFB1 with hepatitis, especially in the adult mice, confirms that the underlying alterations in the hepatocytes are essential for manifestation of the tumor-promoting effects of AFB1.

Although genetic alterations in epithelial cells are essential for the development of premalignant lesions, recent studies have shown that the nature of the tumor microenvironment and circumjacent stromal cells, including infiltrated immune cells, can significantly modify the outcome of these alterations [ 9, 10].

The virus does not replicate in the host caterpillar, but viral gene expression and protein production are essential for alterations to the immune system and development of the host leading to successful development of the wasp larvae.