Sentence examples for alterations and no from inspiring English sources
Although targeted therapies are emerging to combat non-small cell lung cancer (NSCLC), the principal type of lung cancer, they are currently limited to a small fraction of tumors with defined oncogenic alterations, and no specific treatment exists against tumors carrying activating mutations in the most frequently mutated proto-oncogene, KRAS.
Rare populations of variant small cell lung cancer cells could be isolated that had additional genetic alterations and no longer underwent irreversible proliferation arrest in response to Hsp90 inhibitors.
The remaining patients developed no neural or vascular alterations and no bronchial stump insufficiency during follow-up.
12– 14 Using Sanger sequencing, we analyzed this mutation in the cases with STX11 alterations, and no mutations were observed (data not shown).
Only a few renal corpuscles had major ultrastructural and structural alterations and no change in serum creatinine or creatinine clearance was observed.
The majority of liver-specific transcripts (Pan et al., 2013) (which roughly represent hepatocyte differentiation state) were strongly repressed in Yaphigh hepatocytes from CCl4-treated mice, whereas WT and Yaplow hepatocytes showed minimal alterations and no bias towards decreased expression.
Enright and his team hash out a narrative, subject to alteration, and "no zones" like work and home.
The expression of human four-repeat tau with G272V and P301S mutations under a Thy1.2-promoter induced neurofibrillary pathology in the brain with severe cognitive alteration and no sensorimotor deficit [ 270].
Often the ultimate aim is to produce a virus that has the desired phenotypic change and no additional alterations in characteristics.
In addition to the principal evaluation criteria, the reviewers are asked to give a final publication recommendation: "Do you recommend acceptance of the manuscript?" Here, the response categories are: (1) yes, without alterations, (2) yes, after minor alterations, (3) yes, after major alterations, and (4) no.
Results demonstrate that AEPa effectively promotes antileishmanial activity with several important morphological alterations and has no cytotoxic effects on host cells.
