The phrase "alterations and associated" is correct and usable in written English.
It can be used when discussing changes or modifications along with related elements or factors.
Example: "The report includes details on the alterations and associated costs for the project."
Alternatives: "modifications and related" or "changes and corresponding".
These extracellular mediators activate a carefully orchestrated sequence of intracellular signals resulting in a system-wide coordinated program of gene expression alterations and associated changes in the functional state of the liver cells [ 1- 4].
Detailed knowledge of epigenetic alterations and associated molecular mechanisms during pancreatic tumorigenesis and metastasis will broaden the biological understanding of the disease and help devise novel targets for earlier diagnosis and increasingly effective therapies.
Table 1 describes the multiple hallmarks of cancer pathogenesis, respective cellular and molecular alterations, and associated targeted therapies.
They found a pattern of copy number alterations and associated expression change that could identify poor-prognosis oesophageal adenocarcinoma.
After sequencing the human genome, numerous projects have focused on characterizing genomic alterations and associating them with the different diseases or functional elements of the genome.
It is becoming clear that a given genetic alteration and associated molecular changes involving particular pathways in the neoplastic cell may not necessarily be specific for that particular type of cancer.
The other subtype non-3q8pq200) lacks these copy number alterations and is associated with a low risk of metastasis (7%).
We also examined relationships between these metabolic alterations and those associated with advancing age in HIV-negative controls.
Epigenetics alterations are involved in the pathogenesis and progression of kidney disease, especially because these alterations are easily promoted by the plethora of coexisting metabolic alterations and inflammation associated with CKD [ 34].
Acute increases of blood glucose concentrations and fluctuating glucose levels with high peaks may induce hemodynamic alterations and are associated with endothelial dysfunction and signs of oxidative stress, even in non-diabetic patients.
Our data showed that three mutations of IVS3+2T>C in SPINK1 gene, M470V and c.2562 T>G in CFTR gene had relatively higher frequencies than other genetic alterations and were associated with clinicopathological data.
