Sentence examples for alterations and an from inspiring English sources

Therefore, molecular imaging using positron emission tomography (PET) could be advantageous in this setting since biological changes usually precede morphological alterations and an early tumour-specific response could be defined.

By generating genetic diversity, CIN may provide cells with an increased probability of acquiring tumor-promoting alterations and an increased adaptive potential when challenged by treatment.

There are several studies that established the influence of anemia and abnormal coagulation, hemostatic alterations, and an increased bleeding tendency [ 31- 33].

The carcinogenesis of breast cancer is a complex multistep process associated with numerous genetic alterations and an early hematogeneous dissemination of tumor cells [ 2- 4].

Consequently, solid tumours at diagnosis are generally characterised by complex karyotypic alterations and an increasing number of chromosomal aberrations have been shown to be associated with tumour development and progression (reviewed by Albertson et al (2003)).

The building was subsequently given landmark status, protecting it against major alterations, and a court battle over that designation dragged on until it was upheld by the Supreme Court in 1991.

Thomas Jefferson's profile remains on the coin's front side, with some slight alterations, and a bison appears on the other side, to mark the bicentennial of the Louisiana Purchase and the Lewis and Clark expedition.

Genetic alterations and a chaotic tumor microenvironment, such as hypoxia, acidosis, free radicals, and cytokines, are clearly attributed to numerous abnormalities in the expression and signaling of VEGF and its receptors.

Moreover, both aquaporin-4 and Kir4.1 stainings of the knockout retina (Fig. 1E',F') showed morphological alterations and a disturbed retinal layering.

Indeed, Purkinje cells underwent morphological alterations and a degeneration of dendritic branching.

More alterations and a higher frequency of large alterations (entire chromosome arms deletion or amplification) were found in the EGFR mutated group suggesting that carcinogenesis pathways are different.