The phrase "alterations and additional" is not correct as it is incomplete.
It likely needs a noun to follow "additional" to make sense. You can use it in contexts where you are discussing changes and extra elements related to a project or document.
Example: "The contract includes provisions for alterations and additional services that may be required during the project."
Alternatives: "modifications and extras" or "changes and supplementary".
In the current study our aim was to extend these preliminary data on BRCA2 germline alterations and determine additional somatic genetic changes in both BRCA2 carrier and non-carrier male breast cancers.
Therefore, in order to distinguish Iγ1 from the remaining subclasses, PCR was carried out with primers that contained a minimum number of 4 naturally occurring base alterations and 3-4 additional changes that were intentionally introduced into the primer sequence.
The description of the alterations this network presents in association to a certain phenotype can lead to the identification of the most relevant sncRNAs driving these alterations and provide additional information to determine the sncRNAs that could have a central role in the disease.
In addition, maternal, developmental, and postnatal toxicities of PFOS were reported in the rat and mouse (Lau et al. 2003; Thibodeaux et al. 2003), showing that exposure to PFOS of pregnant rats and mice leads to significant physiologic alterations and that additional investigations are required to elucidate the pathophysiologic mechanisms.
Compliance with administration of the treatment was confirmed and, if necessary, dosage alterations were made and additional therapy was added.
An alteration saw the addition of two chimneys and additional alterations to the window and door openings on the northeast and southwest sides of the house.
However, more discrete alterations cannot be discarded and additional experiments using germ-free animals and/or molecular methods for bacterial detection are required to further explore the relationship between Card15/Nod2 and the normal gut flora.
The notion that only a portion of melanocytes with activated ERK will develop melanoma, suggests that the ERK activation is an initial event in GHM genesis and additional alterations are needed for progression to melanoma.
At the single-cell level, most primary tumors are polyclonal due to punctuated clonal evolution where copy number alterations serve as founder mutations and additional CNVs and/or point mutations occur later in tumor development.
Sequential and additional genetic alterations affecting several proto-oncogenes and tumour suppressor genes have been recognised in the pathogenesis of CRC.
