Sentence examples for alterations affecting the from inspiring English sources

With regard to PDAC recently Jones et al. performed a comprehensive genetic analysis leading to the identification of a defined set of partially overlapping signalling pathways that were altered, despite the fact that the alterations affecting the individual component varied widely between individual tumours [34].

To a large extent, these processes are influenced by alterations affecting the integrity of genome architecture and, ultimately, its phenotypic expression.

MLPA is performed in order to identify possible gross genomic alterations affecting the APC gene.

Various genomic alterations affecting the majority of chromosomes were found in cervical cancer cell lines.

However ultrastructural alterations affecting the membrane or the transporter could still be possible and were not evaluated.

Similarly to the other case, he developed bilateral and symmetrical focal alterations affecting the brainstem, hyperintense on T2-weighted images.

With our model, we could explore how an intrinsic factor, i.e., genetic alterations, affects the SC activity, providing unique genome-wide data and direct assessment of the ex vivo performance of SCs of different ages.

Those alterations affected the overall quantum yield of the photosynthetic electron transport in photosystem II.

The systematic analysis of 4 000 induced mutations in Escherichia coli lac repressor, reported in [55], has revealed that 41% of the alterations affect the protein function.

As a consequence of the successive rounds of mutation and selection of cell clones, molecular alterations affect the fundamental processes of a normal cell, such as proliferation, differentiation, and apoptosis [1].

In silico analyses predicted that the novel alterations affect the structure/function of the TPO protein.