The phrase "alteration which could" is correct and usable in written English.
It can be used when discussing potential changes or modifications that may be possible or necessary in a given context.
Example: "The alteration which could improve the system's efficiency is still under consideration by the team."
Alternatives: "change that might" or "modification that could".
Genetic alterations are irreversible alterations, which could be observed as early as in the pre-neoplastic stages.
Overall, these growth alterations could be indicative of underlying functional, physiological alterations which could become apparent in postnatal life.
First, selective pressure on one gene in the region could create linkage disequilibrium that would effectively reduce structural alterations, which could disrupt the synteny.
These HIV-exposed uninfected (HEU) infants may have immunological alterations which could lead to weakened responses to infections and vaccines and vulnerability to disease [ 7].
Hormonal stimulation causes numerous local and systemic alterations, which could render the mammary epithelium resistant to tumorigenesis and not require p53.
Indeed, various biochemical alterations which could be happen during purification [ 7] or through enzymatic degradation [ 26] were shown to reduce the cytokine-inducing capacities of cell wall components.
It is widely accepted that malignant tumours are caused by the accumulation of genetic alterations, which could reflect the biological behaviour of tumours (Cordon-Cardo, 1995).
These abnormalities involve much molecular alterations, which could also be tapped upon for diagnosis, most importantly during routine endoscopic inspection (Lauwers and Riddell, 1999).
Third, as CNVnator may have missed some DNA copy number alterations which could cause abnormal allele fraction, we further performed MLPA on the 19 pSNMs which were validated by both pyrosequencing and clonal Sanger sequencing.
