Sentence examples for alteration required for from inspiring English sources

In that universe, the time coordinate of one coordinate system depends on both the time and space coordinates of another relatively moving system, forming the essential alteration required for Einstein's special theory of relativity.

This is due to the great structural alteration required for the establishment of strong intramolecular hydrogen bonds between axial groups.

He simply delivered the text, usually in the BBC's New York studio, made any alterations required for timing purposes, and went home, leaving the engineers to iron out the coughs and splutters caused by decades of smoking.

To further identify metabolic alterations required for suppression, strains expressing a gene (pgk or pykA) or a group of genes (the whole gapA operon, which includes the suppressive gapA, pgk, pgm and eno genes) of the bottom part of glycolysis under the control of an inducible promoter were constructed.

Somatic point mutations may account for only a fraction of the genetic alterations required for tumorigenesis.

Studies also showed that AR, as a crucial factor, determines the molecular alterations required for the development of refractory prostate cancer (Debes and Tindall, 2004).

For example, we followed this approach to characterize the metabolic adaptations of Mycobacterium tuberculosis to hypoxia and identify metabolic alterations required for adaptation to a lifestyle of low metabolic activity [ 10].

In order to gain insight into the molecular alterations required for vHMEC to progress to malignancy, and to characterize the epigenetic events associated with early progression, we examined the effect of oncogenic stress on the behavior of these cells.

The inefficiency of metastasis is explained in this model by the low probability that any given cell within the primary tumor will acquire all of the multiple alterations required for the successful implementation of the metastatic cascade.

The BRCA1 and BRCA2 defective tumors demonstrate specific pattern of genetic alterations required for tumor genesis; for example, Myb amplification and p53 mutation with different pattern frequently occur in BRCA1 deficient tumors compared to sporadic ones; this is in contrast to Her2 and cyclin D1 overexpression.

In order to gain insight into the molecular alterations required for vHMEC to progress to malignancy, and the epigenetic events associated with that progression, we examined the effect of oncogenic stress on the behavior of HMEC that express p16INK4A, and vHMEC that do not, by expressing constitutively active Ha-rasV12 in these cells.