Sentence examples for alteration point from inspiring English sources

In general, the results reviewed here for the fate of Aβ and apoE after SVD-related BBB alteration point to two different effects of protein retention in the brain (1) accumulation, as documented for Aβ, and (2) degradation as presumed for apoE.

These behavioral alterations point to defects beyond the locomotion system and may reflect a more global function of CHN-1, as expected for a CHIP homolog in a higher eukaryote32.

Some of these alterations point towards a peroxisomal dysfunction.

Indeed, some of the observed mRNA alterations point out changes characteristic for oxygen deprivation.

All these molecular alterations point toward a possible implication of Twist1.

We then analyzed the association between recurrent somatic alterations (point mutations and SCNAs) and number of rearrangements.

Also, genome-scale approaches to study the epigenetic alterations point out a possible association of global hypomethylation and different neurological disorders as schizophrenia or bipolar disorder [ 8, 9].

Most of the current driver identification approaches aim to uncover somatic alterations, point mutations in particular, that occur at a statistically significant rate in cancer.

These alterations point to those enzymes involved in the biosynthesis of the glycosaminoglycan chains and to both their regulation and enzymatic activity as potential modifiers of this process.

As some of these alterations point towards a peroxisomal dysfunction, we investigated peroxisomes in human postmortem brains obtained from the cohort-based, longitudinal Vienna-Transdanube Aging (VITA) study.

Whole genome sequencing (WGS) based on NGS techniques offers the possibility to identify the complete range of genomic alterations: point mutations, indels, copy number changes, and structural rearrangements including translocations, cryptic rearrangements, inversions and complex rearrangements in the whole genome.