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This was reflected in the quantitative alteration of various biomolecules and bioaccumulation of the toxic metals even in the tissues of APE and LPE-exposed fish.
Hence, spontaneous PCD in atips1 may result from the alteration of various inositol-related signalling pathways.
The severe damage of chloroplasts and reduction in photosynthetic activity might be connected with alteration of various agronomical and morphological traits in the type necrosis lines (Table S3; Fig. 2).
The disruption of functional CAMTA protein in mutant resulted in alteration of various regulatory pathways and stress responses (Additional file 10).
The persistently activated STAT3 proteins in tumour cells promote a permanent alteration of various oncogenic genes that control cellular processes such as proliferation, survival, invasion, angiogenesis and chemoresistance (Wang et al, 2011).
Genotoxins lead to alteration of the internal antioxidants and antioxidant enzymes like superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and glutathione reductase (GR) along with alteration of various important body functions resulting in damage to tissues and membranes.
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Taken together, numerous studies in a variety of tumor entities show statistical correlations between patient prognosis and alterations of various markers compatible with EMT.
In fact, lack of CFTR at the plasma and subcellular membranes may affect biophysical properties, thereby culminating in alterations of various functions, including lipid synthesis and transport.
In response to oxidative stress, alterations of various endosomal-lysosomal components including ARSB have been observed in AD brains [60], [61].
Finally, as alterations of various steps in yolk production are also associated with an egg collapse phenotype [32], [33] we tested the localization of the vitellogenin receptor, Yolkless, in mutant egg chambers in order to assess vitellogenin endocytosis.
Alterations of various signaling pathways may result in deregulation of apoptosis, leading to cancer.
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