Suggestions(5)
Exact(6)
Systemic inflammation may cause ACLF through complex mechanisms including an exaggerated inflammatory response and systemic oxidative stress to pathogen- or danger/damage-associated molecular patterns (immunopathology) and/or alteration of tissue homeostasis to inflammation caused either by the pathogen itself or through a dysfunction of tissue tolerance.
Retardation or acceleration of differentiation during immune adaptation may cause a permanent alteration of tissue function.
Alteration of immune physiology can by itself cause alteration of tissue function (immune pathology), such as rheumatic [ 19] and degenerative diseases [ 20].
Furthermore, the alteration of tissue specific gene expression by DNA methylation may lead to the progression of many disease states, including cancer.
The shoulder joint also showed a reduction in the joint line, and a similar alteration of tissue organization as seen in the elbow was found in the scapula humerus interface of the shoulder joint (Figs. 4T W).
This module is enriched with genes normally expressed in macrophages suggesting either the influence of Kupfer cells in the liver or general alteration of tissue macrophage response to atherosclerotic stimuli.
Similar(54)
However, alterations of tissue perfusion, source of cellular hypoxia, can coexist with optimal macrocirculatory parameters.
Seventy percent of the Elf3-deficent progeny were born and displayed severe alterations of tissue architecture in the small intestine, manifested by poor villus formation and abnormal morphogenesis and terminal differentiation of absorptive enterocytes and mucus-secreting goblet cells.
Such a mechanism causing alterations of tissue is well-known in liver and lung congestion.
AdNK4 plus DAS (36 days) gave remarkable alterations of tissue architecture, because of extensive intercellular void spaces, suggesting autophagy dysfunction.
DTI, which is sensitive to water diffusion, captures microstructural alterations of tissue by measuring systematic directional changes in water diffusivity.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com