Exact(3)
This study involved normal MPCs (i.e. cells isolated from non-diabetic rats) and the question remains whether diabetes causes alteration of the functional properties of MPCs.
Actin sliding velocity on both myosin and heavy meromyosin fraction (HMM) of Atg7 −/− was slower compared to controls, confirming that an alteration of the functional properties of contractile proteins occurs when autophagy is reduced.
We conclude with the suggestion that our approach and the resulting data indicate a novel mechanism of SNP action: alteration of the functional characteristics of the proteins through phosphorylation may significantly contribute to our understanding of the molecular basis of complex diseases, such as cancer.
Similar(57)
The aim of this study was to investigate the alterations of the functional connectivity of neural network and their frequency specificity in migraineurs as compared with healthy controls by using magnetoencephalography (MEG) and concepts from graph theory.
It has also been associated with a greater use of health system services, greater clinical findings at assessment associated with a negative mood [24,25], and alterations of the functional mandibular status [1].
Hans et al. (2008) observed that the solution to the problems posed by disability must be achieved by policy changes that affect the environment, rather than by an exclusive reliance on alterations of the functional or economic capabilities of individuals with disabilities.
Original neurophysiologic evidence is provided for alterations of the functional activation brain states after sleep.
Various researchers (Ryan et al. 2008a, b; Mizuno et al. 2013) pointed out a dose and time-dependency of static stretch with alterations of the functional parameters of the muscle tendon unit.
Thus, we assume that the increased microvascular proliferation in endometrial carcinoma tissue detected has its correlate in specific alterations of the functional status of the tumour vasculature in vivo, with potential relevance for tumour progression and metastatic spread.
Therefore, a study using various frequency bands is required for further analysis of alterations to the functional characteristics in patients with aMCI and AD.
We hypothesize that initially an individual connection can be changed, while the network is in an unbalanced state, and that internal forces will then drive the network into a new balance that may or may not contain the alteration of the selected functional connection.
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