The phrase "alteration of the function" is correct and usable in written English.
It can be used in contexts discussing changes or modifications to a specific function, often in technical or scientific discussions.
Example: "The alteration of the function in the software led to improved performance and user experience."
Alternatives: "modification of the function" or "change in the function."
A recent functional study provided evidence for an alteration of the function of the ATP-sensitive potassium channel in the β-cell, encoded by KCNJ11 and ABCC8, when these two variants were coexpressed [ 77], possibly explaining previous inconclusive reports of investigations of a single mutation.
We used this assay system to evaluate the effect of an alteration of the function of ATMSH2, the Arabidopsis homologue of MSH2, on microsatellite stability.
We replaced the two loops with segments of random amino acids, and used mRNA display to isolate variants that specifically recognize adenosine triphosphate (ATP), demonstrating a significant alteration of the function of this protein domain from DNA binding to ATP recognition.
Alteration of the function of key components of the TGFβ/Smad signaling by using RNA interference or decoy ligand traps approaches impairs the formation of breast cancer metastasis in experimental models [ 16, 25, 26].
This silencing effect contributes to an alteration of the function of genes located near the ring fusion point by modulating (mainly downregulating) their expression in a telomere-dependent fashion [ 10, 16- 18].
The first hypothesis takes into account the well described alteration of the function of the major Pi transporter, Mir1p, when a single cysteine residue is modified (see Additional file 5).
This could occur either through acetylation-dependent alterations of the function of non-histone proteins, including transcription factors such as STAT380, or by metabolite changes that could result from decreased acetate availability.
APE1 gene polymorphisms may lead to amino acid substitutions, which may result in alterations of the functions of APE1/Ref-1.146.
Long-term consumption of Con A reduced food efficiency suggesting the alteration of the digestion/absorption function of the intestine in the presence of lectin.
Another interesting point regarding this case is the alteration of the liver function.
Therefore, the progressive alteration of the mitochondrial function may limit ROS production despite the observed increase in the mitochondrial mass.
