The phrase "alteration of substrate" is correct and usable in written English.
It can be used in contexts related to biology, chemistry, or materials science, where changes to a substrate are being discussed.
Example: "The alteration of substrate in the experiment led to unexpected results in the reaction rates."
Alternatives: "modification of substrate" or "change in substrate".
In two riffle-pool construction projects studied, modification of the channel gradient showed a greater effect on DSW than the alteration of substrate texture.
In the light of structure-based mapping of the active site, activity assays, mutagenesis studies and a first structure-guided alteration of substrate specificity towards bis- 2-hydroxyethyl) terephthalate (bis- 2-hydroxyethyl, we anticipate MHETase to bis- 2-hydroxyethylrce terephthalatevance enzymatic plastic degradation.
Interpretation of the effect of the replacement of Asp167 to Glu on the alteration of substrate specificity in relation with the predicted 3D model of PQQGDH-B is also discussed.
Although the engineering of glycosyltransferases is still in its early stages, recent work on the structure-based alteration of substrate specificity and the manipulation of glycosyltransferase profiles in whole cells to effect complex changes in in vivo glycobiology probably foreshadows a wave of considerable innovation in this area.
Our research reveals that the architecture of biofilm formation by a single strain of bacteria varies in response to alteration of substrate and conditioning layer.
Therefore, it is likely that the positive selection exerted here during evolution resulted in alteration of substrate specificity of MelD2.
Negligible aesthetical alteration of substrates and ease of application additionally prove that significant contribution can be made by similar treatments in future nationwide retrofit projects.
The major factors useful in controlling enzyme activity are: temperature, water activity, pH, chemicals which can inhibit enzyme action, alteration of substrates, alteration of products and pre-processing control.
Our structural and mutational analyses shed light on the substrate recognition using an induced-fit mechanism and enabled first structure-guided alterations of substrate specificity of MHETase.
It was suggested that the binding of CBP21 to chitin led to the disruption of the crystalline substrate structure through specific polar interactions that were not only important for binding, but also for alteration of the substrate structure [ 29].
Gypsum and nitrates detected by FTIR spectroscopy in the superficial areas of the samples are due to environmental contamination whereas no significant signs of chemical alteration of the substrate (sulphation) are observed.
