Sentence examples similar to alteration of site from inspiring English sources

To ascertain the nature of these splicing anomalies two artificial variants were designed and generated: c.8484A > T (intact splice site and SF2 disruption) and c.8486A > C (weak alteration of splice site: 0.95 →0.92 and SF2 disruption; Additional file 1, Table S1).

The provincial government designated the slide area a restricted development zone in 1976, which prevents alteration of the site.

The derivative plasmid was obtained by the deletion of a 4,3 kb NotI fragment containing the kanamycine cassette flanked with the two IS10 sequences and ats1ats2 sequences (alteration of target site recognition).

RNA studies to detect possible alteration of splice site, revealed no changes in RNA size for this change [ 20].

The presence of this intron in so many Syt genes could be interpreted as evidence that evolutionary alteration of this site is hazardous.

Inherited resistance to chemical insecticides in mosquitoes is mainly the consequence of two distinct mechanisms: the alteration of target sites inducing insensitivity to the insecticide (target-site resistance) and/or an increased metabolism of the insecticide (metabolic-based resistance) [ 8].

The major mechanisms of insecticide resistance already described in several insects involve the alteration of target sites inducing insensitivity to the insecticide (target-site resistance) and/or an increase in the rate of insecticide metabolism (metabolic resistance) [ 5].

However this alteration of branch-site recognition may not induce any functional difference because the branch-site adenosine is still free to attack the 5'-guanosine phosphate.

Biofilm formation [12] and alteration of binding sites of drug [13] are the mechanisms of acquiring resistance to vancomycin.

We tried to recover GBSSI using F/M primers in Taeniatherum, but amplifications failed several times, probably due to alteration of primer sites.

Disruption or alteration of binding sites for auxiliary splicing factors as well as of other gene regulatory regions promoter and 3′ UTR may affect mRNA transcription, processing and translation, in turn playing a pathological role.