The phrase "alteration of sequence" is correct and usable in written English.
It can be used in contexts where changes or modifications to the order of elements, events, or processes are being discussed.
Example: "The alteration of sequence in the experiment led to unexpected results that required further investigation."
Alternatives: "change in order" or "modification of arrangement".
Consistent with this, all twelve mapped hedgehog mutations either affected the structure of the N product directly or otherwise blocked the release of N from the Hh precursor as a result of deletion or alteration of sequences in the C domain.
The alteration of sequences to induce base-paring throughout the region of 6S RNA also results in producing an inactive RNA, suggesting that the structure is crucial [ 8].
Thus, whereas HR is considered error-free, both SSA and NHEJ may result in mutagenic alteration of sequences at the DSB.
We have described a new "subtle" splicing isoform for CYYR1 locus and alterations of sequence and expression of this gene in a large series of NE tumors.
It has long been thought that disease causing variants act through alteration of exon sequence resulting in altered protein function.
We also review the current knowledge of functional mutations that act in ways other than alteration of protein sequence, such as mutations that alter gene expression or splicing.
However, alteration of a sequence of the 6 base pairs containing stem of MB allowed the design of pHSO probes that exhibited different dynamic pH range and possessed slightly different transition midpoint between i-motif and open loop configuration.
We found a half TRE (AGGTCA) in this region, but alteration of this sequence to AGATCA by site-directed mutagenesis had no effect on the transcriptional activity in vitro (data not shown).
Causes of aberrant behavior include alteration of DNA sequence (genetic) and alteration of gene expression (epigenetic regulation).
