The phrase "alteration of proinflammatory" is correct and usable in written English.
It can be used in contexts discussing changes or modifications related to proinflammatory processes or factors, often in scientific or medical discussions.
Example: "The study focused on the alteration of proinflammatory cytokine levels in response to the treatment."
Alternatives: "modification of proinflammatory" or "change in proinflammatory".
The fact that only a small number of smokers develop COPD may be based on genetic alterations of common proinflammatory cytokines such as CRP and IL-6.
Furthermore, alterations in the concentration of proinflammatory mediators have been described in SLE patients such as cytokines known by their potential role on bone metabolism [57, 58].
This trial is also examining potential mechanisms responsible for this neurotoxicity including alterations in circulating levels of proinflammatory cytokines as well as fluctuations in stress and sex hormones.
Still's disease is a rare systemic inflammatory disorder of unknown etiology characterized by quotidian spiking fevers, evanescent rash, arthritis, and elevated acute-phase reactants in the serum linked to alterations in the production of proinflammatory cytokines.
Moreover, alteration of the spinal concentration of proinflammatory cytokines, tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) was studied.
In particular, Zager and Johnson demonstrated the upregulation of histone-modifying enzyme systems and the alteration of histone expression at proinflammatory and profibrotic genes such as TNFα and monocyte chemoattractant protein-1 in IRI [ 56- 58].
However, the association between cellular expression of proinflammatory cytokines, alterations of sleep depth and daytime fatigue has not been concurrently examined.
The findings of the reported study presented that suilysin-positive strain could show toxin to produce functional alteration and increase the permeability of BBB; and Suilysin-negative strain might stimulate the production of proinflammatory cytokines resulting in alteration of BBB permeability [ 76, 77].
These findings imply that other factors within the local joint environment, perhaps alterations in osteoblast function or expression of proinflammatory cytokines such as TNF-α, may act in concert with these soluble mediators of bone remodeling to promote osteoclastogenesis, and, in turn, bone erosion.
SM extract administration also attenuated the release of proinflammatory cytokines and prevented alterations of TLR4 signaling in the hippocampus induced by chronic BCCAo.
