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The lesions initially displayed keloid features, with traction on the underlying tissues and consequent retraction and loss of elasticity of the cutaneous layers, lymphoedema of the surrounding tissue associated with alteration of normal skin pigmentation to a reddish-violet colour.
The fundamental shape change is alteration of normal relationships between the transverse basal loop and oblique apical loop, to make the apical loop become more basal through more transverse fiber orientation.
Alteration of normal scapulohumeral rhythm due to the fatigue of scapular-stabilizing muscles induces decrease of rotator cuff strength.
Previous experimental studies of the encircling endocardial ventriculotomy (EEV) have shown a significant alteration of normal local electrical activity within the encompassed region.
Post-traumatic deformity results in alteration of normal anatomy, biomechanics of distal radius, and functional impairment in hand and wrist [6, 7, 8].
However Kreso et al. described a new therapeutic way to downregulate the BMI1-related self renewal without alteration of normal stem cells [55].
Similar(33)
Understanding disease all stems from identifying alterations of normal anatomy.
Dysmorphology refers to alterations of "normal" or typical morphology that can be observed and/or measured in a population.
The repeated failure of therapeutic approaches based on this dogma in humans suggests that alterations of normal APP functions may contribute to AD pathogenesis.
This effect is primarily related to the development of obstructive hydrocephalus and alterations of normal cerebrospinal fluid flow-dynamics.
It is not known whether these processes would lead to PTB; however, they are alterations of normal function and may disrupt normal processes of gestation.
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