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In future studies we will investigate the "relative" network properties by constraining each network with the same number of nodes and connections to further investigate the alteration of network organization in the blind subjects.
A very intriguing additional possibility is active alteration of network properties by employing molecular motors such as actin-associated myosins.
It is also unclear if and how SWD will influence the within/between module network dynamics, a question should be addressed in the future with simultaneous EEG with fMRI and with new-onset epilepsy patients [ 35], from which the causality between the alteration of network connections and seizures could be resolved.
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The results indicated an alteration of networks related to the inflammatory response and to cell death and survival.
Dynamical network biomarkers (DNB) show time-dependent alterations of network biomarkers monitored and evaluated at different stages and time points during the development of diseases [12].
By using functional connectivity and graph theoretical techniques, the present fMRI study investigated the global alterations of network properties in mTLE.
Results revealed alterations of network properties including a change in the degree distribution, reduced overall strength in connectivity, and increased "small-worldness" from 3 months to 6 months post injury.
Instead, homeostatic alterations of network excitability were triggered directly by suppressed synaptic activity.
These indirect and direct alterations of network copy numbers have the potential to change the output or activity of a gene network.
Changes in neuronal properties and resulting alterations of network behavior constitute one of the important mechanisms of epileptogenesis (Yaari and Beck, 2002; Noam et al., 2011; Goldberg and Coulter, 2013).
Several studies investigated the activity of the resting state functional networks in migraine and found various alterations of networks that are implicated in pain processing [16 19].
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