Sentence examples for alteration of mutant from inspiring English sources

The phrase "alteration of mutant" is correct and usable in written English.
It can be used in contexts discussing changes or modifications to a mutant organism or genetic material.
Example: "The alteration of mutant genes has led to significant advancements in our understanding of genetic disorders."
Alternatives: "modification of mutant" or "change in mutant".

Exact(2)

Previous electrophysiological studies described the alteration of mutant sodium channel gating and demonstrated its responsibility for the phenotype [ 3, 4].

The implications of our findings may lead to new therapeutic targets for HD, including: alteration of mutant huntingtin nuclear localization in response to stress; inhibition of TG2 enzymatic activity (67) or activation of alternative stress response pathways that override or circumvent the function of the huntingtin protein in actin-mediated cell stress response.

Similar(58)

The functional expression of the mutations in expression systems allows to study the functional alterations of mutant channels and to develop new strategies for the therapy of ion channelopathies, e.g. by designing drugs that specifically suppress the effects of malfunctioning channels.

We further evaluated the alteration of PD mutants in 14-3-3 14-3-3 14-3-3tro.

In a search for copy number alterations of PTPN11 mutant alleles, we performed sequence analysis in tumor DNA of 9 out of 12 patients diagnosed with a malignancy.

The current explanation for the development of therapy resistance and tumour recurrence invokes genomic alterations and selection of mutant cells carrying a relevant mutation acquired by chance before therapy (Nowell, 1976; Yachida et al, 2010; Sottoriva et al, 2013).

This result is consistent with the absence of GP activity in P1 muscle, and might indicate an alteration in the translation of mutant mRNA or changes in the stability of the mutant protein.

Analysis of cholesterol metabolites in patient cell line extracts showed no significant alteration in the presence of mutant protein indicating a potentially novel function of the UBIAD1 protein in cholesterol biochemistry.

A mechanistic model based on auxin fluxes successfully predicted this property and the phenotype alteration of auxin transport mutants or plants with modified rythms of lateral root initiation.

Alteration of selected color mutants in the six-gene cluster was screened by PCR using primers that covered the whole region.

Variation of phenotype strength may explain frequencies of mutant alterations sharply below 25% within some crosses (curly, levi, smerz) (Table 2).

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