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The phrase "alteration of genome" is correct and usable in written English.
It can be used in discussions related to genetics, biotechnology, or any context involving changes to an organism's genetic material.
Example: "The alteration of genome sequences has opened new avenues for medical research and treatment."
Alternatives: "genomic modification" or "genetic alteration".
Exact(3)
However, GC clusters have been suggested as mtDNA recombination hotspots (Dieckmann and Gandy 1987), and GC cluster mediated gene conversion can insert or delete large genomic fragments, which ultimately lead to substantial alteration of genome size.
Four classes of events are found to drive SSR variations: insertion/deletion of SSR units, expansion/contraction of SSRs without alteration of genome length, changes of repeat motifs, and generation/loss of repeats.
Epigenetic mechanisms allow alteration of genome function without mutating the underlying sequence.
Similar(57)
However, Southern blot analysis of AAV preparations with heterologous ITR revealed no evident alterations of genome integrity (Fig. 3A).
However, the studies on autopolyploidization aimed at identifying the alterations of genome expression patterns are relatively less than those on allopolyploidization.
Despite the environment factors such as smoking and occupational exposures, it is now widely accepted that genetic and epigenetic alterations of genome are associated with bladder cancer risk.
Thus, most alterations of genome sequence that accumulate within a host would be expected to have a minimum adverse consequence for bacterial expression patterns within the host, while infrequently increasing fitness of the mutant individual.
Thus, the alterative expression of DNMTs might contribute to the alterations of genome-wide methylation in GC-2 cells.
We observed whether 50 Hz ELF-EMF exposure can induce the alterations of genome-wide methylation and the expression of DNMTs in GC-2 cells.
These results suggest that the alterations of genome-wide methylation and DNMTs expression may play an important role in the biological effects of 50 Hz ELF-EMF exposure.
In conclusion, we demonstrated that 50 Hz ELF-EMF exposure can induce the alterations of genome-wide methylation and the expression of DNMTs.
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