Sentence examples for alteration of function from inspiring English sources

Moreover, the functional divergence between orthologs and paralogs (sub-/neo-functionalization of paralogs) or alteration of function during long evolutionary distances 13 suggests that those tests are biased toward single copy genes or conserved families and less suited for large diversified families.

Orai3 knockdown at the onset of EACH limits cardiac hypertrophy, accelerates alteration of function and dilation and promotes fibrosis.

Differences in expression patterns suggest a gain or alteration of function in duplicated B. rapa genes.

This may be caused by our definition of true SDPs, as all residues, whose mutation resulted in alteration of function [ 21].

In addition, alteration of function could also result from the presence or absence of protein-processing enzymes responsible for the activation/deactivation of the enzymes [ 6].

Besides the pain and general discomfort arising from injuries or wounds there may be alteration of function which interferes with the individual's ability to carry on with daily life activities.

Germline point mutagenesis by ethylnitrosourea can provide alleles for a gene of interest that include loss-, gain-, or alteration-of-function.

From this premise, they inferred that no such system could have come about through the gradual alteration of functioning precursor systems by means of random mutation and natural selection, as the standard evolutionary account maintains; instead, living organisms must have been created all at once by an intelligent designer.

For instance, it is still unclear how the HCV mediated pathogenesis is involved in the HCV inactivation and alteration of functions of B cells and hepatocytes during acute and chronic HCV infection.

Early alterations of function are of interest since they may contribute to the development of irreversible pathological events.

Alterations of function relevant to neuronal support could be masked by other sources of S100B production.