The phrase "alteration of enzyme" is correct and usable in written English.
It can be used in scientific or medical contexts when discussing changes or modifications to enzymes, such as in biochemical research or studies.
Example: "The alteration of enzyme activity was observed after the introduction of the new substrate."
Alternatives: "modification of enzyme" or "change in enzyme".
Serine mediated hydrolysis/cleavage by the enzyme has been highlighted and alteration of enzyme configuration under varying pH induced by nanoclays has been projected.
Because the curing involves rearrangement of structural proteins and cross-linking of the proteins for stability, alteration of enzyme activities could change the properties of the glue.
Such reactions lead to alteration of structure of proteins or alteration of enzyme functions.
The most common modulation of biosynthetic enzyme activity is the alteration of enzyme amino acid sequences, which results in enzymes with either enhanced or reduced activities.
To date, sequencing remains the ultimate proof for mutations that lead to amino acid changes and subsequently an alteration of enzyme structure [ 29].
Fluorescence binding assays indicate a significant loss of binding and alteration of enzyme regulation for individual mutants of these surface residues (E16, F17, and E20).
Following the alteration of enzymes involved in lipid biosynthesis in the gene expression profiling of the alloplasmic line carrying the H. chilense cytoplasm, a fatty acid analysis was carried out for this alloplasmic line and its euplasmic control.
Biochemical confirmation is most often seen in alterations of enzyme activity of one or a combination of the respiratory chain complexes.
One renal cell carcinoma tissue showed a somatic A3243G mutation, which is a known frequent cause of MELAS syndrome (mitochondrial encephalomyopathy, lactic acidosis, stroke-like episode) and specific compensatory alterations of enzyme activities of the respiratory chain in the tumour tissue.
Known molecular mechanisms of drug resistance in fungi include overexpression of genes that encode drug-efflux pumps belonging to the ABC (ATP-binding cassette) family of transporter proteins [4], overexpression or mutation of the target enzyme, and alteration of other enzymes in the same biosynthetic pathway as the target enzyme [5].
They could occur via the effects of isoflavones on endogenous estrogen synthesis, through alterations of enzymes involved in steroid metabolism, including aromatase (Rice et al., 2006), 17β-hydroxysteroid dehydrogenases, steroid sulfatases and sulfotransferases (Lacey et al., 2005).
