It is generally known that alteration of cardiac contraction is one of the main causes of cardiac remodeling leading cardiac hypertrophy.
Our study was an attempt to identify the effect of AZL on alteration of cardiomyocyte contraction and related calcium regulatory proteins, which might explain the effect of AZL on cardiac performance under diabetic conditions.
During the last decade there was accumulating evidence that alterations of excitation-contraction coupling (EC) may play a critical role in the pathophysiology of myocardial failure.
In agreement with the majority of researchers, it was of no surprise that soleus did not present any alteration in its time course of contraction, as its contractile properties are not significantly altered throughout early postnatal life.
To investigate whether AEtLP treatment could affect the regulation of proteins related to muscle contraction, alteration of mAchR M2, mAchR M3, PI-3K and PKC expression was observed in the transverse colons of constipation rats using specific primers and antibody.
BPA promotes arrhythmogenesis and enhances myocyte contraction via alteration of myocyte Ca2+ handling (Yan et al. 2011).
Capsule responses to immobilization was dynamic and characterized by modulation of at least three reaction pathways; down regulation of triglyceride biosynthesis, alteration of extracellular matrix degradation and muscle contraction gene expression.
The β2-adrenoceptor agonist, salbutamol, blocked the increase in airway resistance in the OVA-exposed mice overexpressing smad2 (Fig. 3E), demonstrating a pivotal role of smooth muscle contraction in the alteration of lung function.
When exposed to phenylephrine (PE), the specimen contracted immediately and reached maximal within a few min without alteration of EC [Ca2+]i (Fig. 1c, initial contraction phase of Fig. 2).
The tone responds to alterations in perfusion pressure in such a way that when the pressure falls the degree of contraction is reduced, preglomerular resistance is lowered, and blood flow is preserved.
