Sentence examples for alteration of complement from inspiring English sources
Interestingly, Ito et al. (1997) [ 17] have reported that macrophage activation and an alteration of complement factor C3 is necessary for the induction of an anti-tumor effect when A. brasiliensis polysaccharides are used.
Other validated findings include olfactory impairment in the stria terminalis (ST) (module 32) [ 49]; alteration of complement pathways in the MPFC (module 20) [ 50] and activated coagulation function in the ST (module 31) [ 51].
This includes associations of the genetic variants with alterations of complement activation or with certain AMD subtypes, as well as their possible influence on AMD progression, response to treatment (pharmacogenetics), or interference with known modifiable risk factors for AMD (gene-environment interaction).
One exception was the specific alteration of the complement system.
Previous studies have documented alterations of the complement pathway in human hepatitis C; indeed, plasma C3 has been proposed as a marker for activity in this disease [ 24].
In liver tissue of cows with SCE, alterations in gene expression revealed an activation of complement and coagulation cascade, steroid hormone biosynthesis, apoptosis, inflammation, oxidative stress, MAPK signaling, and the formation of fibrinogen complex.
They differed in the extent of complement deposition, granulocyte infiltration, acute astrocyte alterations, astrocyte loss, demyelination and axonal injury.
Starting from the first reports of complement disease-associated mutations [ 1], genetic alterations in four CFH (complement factor H), CFI (complement factor I), MCP (membrane cofactor protein) and complement C3 have increasingly been associated with immune disorders [ 2– 4].
In NMO this alteration of astrocytes seems to be directly induced by AQP4 antibodies in the absence of complement.
Kinoshita, T. Biology of complement: The overture.
Inappropriate activation of complement is normally prevented by complement inhibitors.
