Sentence examples for alteration of collagen from inspiring English sources

This is an indicator of microstructural alteration of collagen.

This difference could be due to the structural alteration of collagen and its deformation with advanced tumour grade.

Here we show, in patient samples, that the effect is predominantly stromal remodelling with marked alteration of collagen architecture and elimination of CAF.

In contrast, μFE analysis did not show any effect of treatment on stiffness, potentially due to the fact that the alteration of collagen cross-links was combined with preservation of the mineralization parameters as described by qBEI analysis.

This age-dependent alteration of collagen fibrils is largely driven by elevated expression of matrix metalloproteinase one (MMP-1) (Fisher et al., 2009), which initiates cleavage of collagen fibrils in skin.

As a consequence, the apparent tissue remodelling in degenerated discs coincides with significant cell matrix changes, including the decrease of collagen content, alteration of collagen distribution, the increase of collagen cross-links and a decrease of proteoglycan levels, which may significantly affect the biomechanical properties of the spinal column.

We characterized microscale morphologic alterations of collagen remodeled by SMCs in six dimensions: three spatial, time, multichannel and multi-position dimensions.

On the other hand, epigenetic alterations of collagen genes have been reported in various neoplasms.

Fibrosis is associated with quantitative and qualitative alterations of collagen deposition within the subepithelial layer of the oral mucosa.

The preceding alterations of collagen and proteoglycan implicate the activation of enzymatic systems, i.e. matrix metalloproteinase (MMPs) and aggrecanase (e.g. a disintegrin and metalloproteinase with thrombospondin type I motif, ADAMTS) [ 1, 2].

The fact that there were no differences in these bone areas between the animals either in mineral content or in maturity/crystallinity suggests that the observed differences in mechanical properties were due to alterations of collagen.