Sentence examples for alteration of at from inspiring English sources

Metabolic diseases and obesity are accompanied by a major alteration of AT functions such as a state of chronic low-grade inflammation in which adipocytes and other AT cells (e.g., endothelial cells, immune cells, preadipocytes) play a role by producing inflammation-related mediators (Goldberg 2009).

The expected outcome of Bmi1 degradation in the presence of SYT-SSX2 is the alteration of at least certain aspects of polycomb silencing function.

Our data indicate that N-cadherin controls osteoblast proliferation and survival via attenuation of autocrine Wnt3a ligand expression and alteration of at least three signalling pathways in osteoblasts (Figure 8D).

If the patient's motor function was rated as improved or deteriorated, an alteration of at least one point on the 5-point scale must have had occurred.

We identified five PTEN mutations in 37 primary prostatic tumours analysed and found that 70% of tumours showed loss or alteration of at least one PTEN allele, supporting the evidence for PTEN involvement in prostate tumour progression.

Comparative microscopic analysis also revealed that first blood meal uptake not only causes an alteration of at least 12 22% of morphological features of the salivary glands but also results in cellular changes e.g. apoptosis, confirming together that adult female salivary glands are specialized organs to manage meal specific responses.

The comparison of the sequences found IVS2-1G>T only in cynomolgus monkey (mfF1, heterozygote), leading to the alteration of AG to AT at the splice site of intron 1.

An interesting study with flupentixol revealed that this drug specifically enhanced the photolabelling of P-gp by [I]-IAAP at the C-terminus, with no alteration of labelling at the N-terminus [ 30].

Of the 100 patients with alterations of at least one gene, 46 (46%), 43 (43%), and 11 (11%) showed alterations affecting one gene, two genes, and three or more genes, respectively.

Of the 122 patients, 100 (81.9%) showed alterations of at least one gene, consisting of either promoter methylation of RASSF1A or DAPK, or mutations in the K- ras or p53 gene.

Importantly, alterations of at least some of the epigenetic modifications, e.g., cytosine DNA methylation, are known to produce transgenerational biological effects which could be relevant to coping with the particular stress condition [ 8- 11].