Strong nuclear reactivity was seen mainly in neurons with alterations of acute hypoxic injury such as condensed and hyperchromatic nuclei and eosinophilic cytoplasm (Figs. 4d, 5).
Taking these and our results into account, a bidirectional influence of SE and systemic inflammation as reflected by alterations of acute-phase proteins and, consecutively, the correlation between acute-phase proteins and SE outcome become more than plausible.
The alteration of these acute phase genes is thought to be responsible for the observed systemic APR phenomena.
The authors'two-hitit' model of cotton smoke inhalation and subsequent instillation of live bacteria is characterized by a hyperdynamic circulation, hypoten-sion, tissue acidosis, and progressive impairment of gas exchange, lung mechanics, and morphological alterations typical of acute lung injury.
Mazzon, E. & Cuzzocrea, S. Role of TNF-α in lung tight junction alteration in mouse model of acute lung inflammation.
Thus in the presence of acute alterations in plasma Ca2+ concentration, NX rats had the ability to restore calcium levels.
C1 INH treatment ameliorated the degree of histological alterations in animal models of acute pancreatitis but did not improve survival [ 35].
To date, the large majority of studies examining epigenetic changes arising from fetal alcohol exposures have employed either chronic models of constant exposure or examinations of acute alterations in chromatin structure [ 5– 7, 10– 122 22– 30].
Routine use of EEGs in acute settings may advance patient care in certain neurological scenarios such as acute alteration of mental status (AMS) and severe traumatic brain injury (sTBI) [2 5].
Grelli, K.N. et al. Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation.
