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Inherent cognitive reserve may mitigate against the emergence of measurable phenotypical alterations before a threshold for functional degradation is exceeded.
Alteration of the threshold for definition of hip OA from 2.5 mm to 2.2 mm reduced the prevalence of OA from 11%to6%6% (Lanyon et al. 2003).
These findings indicate that MUC4 might be responsible for resistance to gemcitabine treatment by alteration of apoptotic threshold in pancreatic cancer cells.
Alteration of low threshold T-type Ca2+ conductances has been reported in DGCs from chronic epileptic rats and human patients (Beck et al. 1998).
The evidence currently available suggests anxious or depressive patients complain more of pain although there is no proof concerning a potential alteration of the nociceptive threshold.
Although the model and observed results were broadly concordant, further manipulation of the iHOMA2 models renal excretion threshold variable (R4) suggested that alteration of the renal threshold by 17% (R4 = 117%) gave the closest approximation for the observed mean decrease of 0.9 mmol/L in glucose.
All the highly quantized DCT frequencies (whose quantization coefficients are greater of a threshold ) are discarded during the embedding because small changes in these coefficients result in large alterations in the respective dequantized coefficients.
The analgesic effect of local heat is similar to the electrical cutaneous stimulation of nerves, which is explained by the gate-control theory of pain or by central alteration of the pain threshold [ 16, 17].
The abandonment of a threshold approach to noncancer risk assessment is an enormous step, and it is important that the underlying assumptions and implications of any new methodology be fully understood before rash alterations are made.
In association with a three chromosomal region predictor, the CGH classifier proposed by Gravier et al. in node negative breast cancer used a measurement of genomic complexity corresponding after segmentation to the total number of segmental alterations along the genome with a threshold of 11.
If region-based tests are repeated under a large series of different models and assumptions, alteration of the significance thresholds would be necessary.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com