Sentence examples for alteration may lead from inspiring English sources

Moreover, FAT1 alteration may lead to modification of ECM stiffness perception during flat muscle fibers development, thus contributing to pathological mechanism of FSHD.

However, mineralogical processes such as (de- carbonatization, silicification, or alteration may leade- carbonatizationfferencesilicificationrorth stalteration Okrusch and maythes 2014).

Future optimization of these compounds through structural alteration may lead to molecules with improved trypanocidal activity and selectivity.

This stress alteration may lead to complications such as femoral neck fractures in patients with osteopenic bone and long-term loosening.

Epigenetic alteration may lead to inactivation of tumor suppressor genes by methylation of CpG-rich regions near the transcriptional start site.

In this sense, deletions, insertions and inversions of DNA coding regions are more dramatic events for genes because such mutational alteration may lead to a reading frame (RF) shift and to modification of the extensive region of amino acid sequence.

The resulting alterations may lead to creation of a new phenotype and, if growth controlling genes are involved, to cellular transformation and the development of tumors.

We then offer a brief introduction to graph theory and describe how this type of mathematical analysis, in combination with computational neuroscience techniques and using parameters obtained from experimental data, can be used to postulate how microcircuit alterations may lead to seizures.

Consequently, these chemical alterations may lead to a potential loss of bonding ability of the adhesive [15].

At the moment, however, it is not clear how these alterations may lead to neurodegeneration.

These KRAS alterations may lead to sustained PI3K signalling and inhibition of p27KIP1 levels.