Sentence examples for alteration is very from inspiring English sources
This strongly supports that SMAD3 alteration is very infrequent and suggests that the MH2 domain is under stringent selective pressure where deleterious mutations impeding proper function could also negatively influence tumorigenesis.
The verdict is not very well; both in terms of storytelling and the alteration of the musical's original structure.
SARs studies indicated that the margins of the structural alteration are very narrow.
Moreover, seeing all three alterations is very rare in IDHmut gliomas, only occurring in 4 % regardless of grade.
It is intriguing that three tumours (#23 25) showed alterations of both IGF2/ H19 and KIP2/ Limprintedntedomainsns, because each domain is independently regulated, and BWS with both alterations is very rare (DeBaun et al, 2002).
Since the list of candidate genes involved in these alterations is very large and has been discussed elsewhere [ 19- 21], we will not elaborate in a detailed discussion of individual candidates.
AKT/PI3K/mTOR pathway alterations are very frequent in bladder cancer, with 73% of human bladder tumours characterised by alterations in one of the major pathway components: TSC1, PI3K (PIK3CA) or PTEN [29].
The essential steps in TMC generation described here are basically in agreement with results of other authors working in MSC transformation [7] [11], [32] and these alterations are very similar to molecular changes associated with transformation of other cell types.
These results suggest that microsatellite alterations are very uncommon in acute myeloid leukaemia.
Some of those alterations are very likely relevant to the carcinogenic process.
