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Examples of direct sequence alteration include premature transcriptional stops and reduced transcription factor binding affinity.
Consequences of the genetic alteration include dysfunctional surfactant processing, ER stress, immune dysregulation, and maintenance of telomere length.
In addition to these, other potential oncogenes that are expressed in the absence of genetic alteration include H- ras, erbB-1/epidermal growth factor receptor (EGFR), erbB-3, and others.
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The mechanisms of metabolic alterations include altered expression, mutation, and posttranslational activation of an enzyme.
Fractures should be characterised by hydrothermal alteration including illite and smectite among others.
A second alteration includes strong chemical and textural changes mainly within and in the immediate vicinity of fractures (Fig. 4).
Throughout the years, the house has undergone significant alteration, including the addition of a gable roof.
Seventeen fetuses were observed to carry a clinically relevant alteration, including 11 sex chromosome aneuploidies and six recurrent microduplication syndromes.
Major alterations include reordering and consolidating departments and increasing the number of computer and video terminals to bring it closer to the state of the art technologically.
The alterations include changes in manufacturing and design efforts, and, of course, job cuts.
Histone alterations include several procedures that regulate transcription, such as acetylation and phosphorylation.
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