Sentence examples for alteration in the regulatory from inspiring English sources
This slight alteration in the regulatory protein, LeMYC2, level in transgenic lines might have attributed to significant changes in the target gene expression.
We now wondered whether the other seven risk genotypes in the model would contribute to alterations in the regulatory microenvironment, for example, the microRNAome.
Our results demonstrate alterations in the regulatory pathway that controls PGC-1α expression and induction of Mfn2 in muscle from patients with early-onset type 2 diabetes.
Alterations in the regulatory mechanisms of apoptosis are, therefore, responsible not only for the progression of breast cancer, but for different response to treatment as well [ 7].
Therefore, attention is turning to potential mechanisms of aberrant Rho activation, such as alterations in the regulatory proteins or aberrant growth factor stimulation.
Since the 1635 G>A SNP at the TLR9 gene causes a synonymous amino acid change but no alterations in the regulatory site, it was suggested that other polymorphisms might affect the immune response against T. gondii as well [ 14].
Given the functional conservation between homologous proteins and regulatory mechanisms among vertebrates, we can speculate that an alteration in this regulatory pathway could be responsible for the hematopoietic phenotype produced by nb/nbl knockdown.
In this situation, protein production is either inhibited or it occurs at an inappropriate time because of alterations somewhere in the regulatory region.
Although sequence variants have been linked to aberrant methylation patterns, no sequence alteration was found in the 5' regulatory region of the gene.
No alteration in the number of regulatory T lymphocytes might enhance their immune-suppressive effect through decrease of other types of T lymphocytes.
Furthermore, it was investigated whether gallstone disease is associated with alterations in the major regulatory transcription factors of the sterol transporters as summarized in Table 3.
