Sentence examples for alteration in the organization from inspiring English sources

On the other hand, we did noticed alteration in the organization of actin filaments in LMP1 expressing cells which is consistent with the previous studies published by Dawson and colleagues who also showed actin filament remodelling following LMP1 expression in 3T3 fibroblasts [17].

The laminar organization in the dorsal spinal cord of Entpd3 -/- mice, as revealed by staining for CGRP and PKCγ and binding of IB4, was indistinguishable from that of WT mice, suggesting that there was no alteration in the organization of primary afferents or spinal neurons in the dorsal horns of mice that lack ENTPD3.

As a result we found that alterations in the organization of synaptic microtubules correlate with reduced protein levels in the microtubule associated protein futsch/MAP1B.

dcc +/− mice exhibit selective alterations in the organization and function of the mesocortical DA circuit and appear to be protected against schizophrenia-like symptoms.

However, we saw no overt alterations in the organization of actin or microtubules in MiTMAB-treated neurons (data not shown), apart from the failure of migrating neurons to resolve their trailing processes at the cell rear.

In support of this idea, it was previously described that NMJ defects similar to TBPH loss of function were found in several other mutants that induce alterations in the organization of the microtubules (MT) at the synaptic terminals [24], [25].

This entire process is mainly supported by the underlying presynaptic cytoskeleton and induced us to hypothesize that alterations in the organization of these structures might explain the morphological defects observed in TBPH mutant alleles.

The idea that microscopic structural alterations in the organization of DHPRs and RyRs within the couplon might play a role in heart failure was first raised in a computer modelling study [12] and this idea has gained traction from rodent studies that have detected a reduced ability of the L-type Ca2+ current to trigger CICR [13], [14].

The evident defects in completing cytokinesis and their multiple attempts to divide led mutant cells to exhibit dramatic alterations in the organization of ciliary rows as confirmed using an antibody against centrin (Figure 4F and G, compare with D and E).

We found no gross macroscopic alterations in the organization of the dorsal horn of Eif4ebp1 -/- mice.

The somitic musculature of CD MPO larvae at 7 dpf presented with evident alterations in the organization.